The American Journal of Physiology - Endocrinology and Metabolism publishes results of original studies about endocrine and metabolic systems on any level of organization. Molecular, subcellular, and cellular studies in whole animals or humans will be considered. Specific themes include mechanisms of hormone and growth factor action; hormonal or metabolite control of organic and inorganic metabolism; paracrine and autocrine control of endocrine cell performance; activation of gene expression; function and activation of hormone receptors; endocrine or metabolic control of ion channels and membrane function; differentiation of endocrine and reproductive cell function; temporal analysis of hormone secretion and metabolism; and mathematical modeling and kinetic analysis of hormone action or metabolism. Novel molecular, immunological, magnetic resonance, or electrophysiological studies of hormone action or receptor activation are also welcome.