|
|
|
Meningococcal Disease: Methods and Protocols |
|
|
|
|
¡Ø±³È¯ ¹× ¹ÝÇ°¾È³» :
- ±³È¯À̳ª ¹ÝÇ°½Ã »óÇ° ¼ö·ÉÈÄ 3ÀÏÀ̳» ±³È¯À̳ª ¹ÝÇ° Àǻ縦 ¾Ë·ÁÁֽðí ÀÏÁÖÀÏÀ̳»¿¡ ÀúÈñÂÊÀ¸·Î »óÇ°ÀÌ ÀÔ°íµÇ¾î¾ßÇÕ´Ï´Ù. ½ÃÀÏÀÌ °æ°úµÇ¸é ¹ÝÇ°ÀÌ ºÒ°¡ÇÕ´Ï´Ù. - º¯½É¿¡ ÀÇÇÑ ±³È¯À̳ª ¹ÝÇ°½Ã, ¹è¼Ûºñ´Â °í°´´Ô²²¼ ºÎ´ãÇϽøç, ¿À¹è¼ÛÀ̳ª »óÇ° ºÒ·®½Ã¿¡´Â ¹«·á ±³È¯ÀÌ °¡´ÉÇÕ´Ï´Ù. - ¹ÝÇ°½Ã¿¡´Â ¹ÝÇ°»óÇ° °Ë¼öÈÄ Ä«µå Ãë¼Ò¸¦ Çص帮°Å³ª ÅëÀå,Àû¸³±ÝµîÀ¸·Î ȯºÒ Á¶Ä¡ ÇØ µå¸³´Ï´Ù. |
|
¡Ø¹è¼Û¾È³» :
- Á¦ÁÖµµ¹× µµ¼»ê°£Áö¿ªÀº Åùèºñ°¡ Ãß°¡µÉ¼ö ÀÖ½À´Ï´Ù. |
|
|
|
|
|
|
|
|
|
Book Info
BC Research Institute for Children's and Women's Health, Vancouver, Canada. Comprehensive and interdisciplinary survey of recent advances and knowledge about this disease. Review-and methods-based chapters provide essential data for diagnosis in the clinical microbiology lab. DNLM: Meningitis, Meningococcal-diagnosis.
Book Description
Andrew Pollard and Martin Maiden bring together a panel of leading authorities to produce a comprehensive, interdisciplinary survey of recent advances and knowledge about meneigococcal disease. The review and methods-based chapters collected here provide essential information for diagnosis in the clinical microbiology laboratory, isolate characterization, clinical management, and control of meningococcal disease. They also examine the immunopathological mechanisms occurring in the acutely ill, host-pathogen interactions, and the possible components of meningococcus responsible for virulence. Meningococcal Disease: Methods and Protocols integrates the basic science, clinical, and epidemiological aspects of this terrible infectious disease to promote the deeper understanding needed to identify novel targets for therapeutic interventions and vaccines.
|
|
|
|
|
|
Foreword Preface Contributors 1 Microbiology and Laboratory Diagnosis 1 2 Isolation, Culture, and Identification of Meningococci from Clinical Specimens 9 3 PCR Diagnosis 23 4 Detection of Meningococcal Antigen by Latex Agglutination 41 5 Meningococcal Serology 61 6 Antibiotic Susceptibility Testing 89 7 Molecular Approach for the Study of Penicillin Resistance in Neisseria meningitidis 107 8 Overview: Epidemiology, Surveillance and Population Biology 121 9 Serological Characterization 131 10 Pulsed-Field Gel Electrophoresis 147 11 Nucleotide Sequencing of Antigen Genes of Neisseria meningitidis 157 12 Multi-Locus Sequence Typing 173 13 Capsular Operons 187 14 Molecular Analysis of the Meningococcal LPS Expression 203 15 Genome Sequencing and Annotation 215 16 Representational Difference Analysis 231 17 Managing Outbreaks: The Public Health Response 257 18 Global Trends in Meningococcal Disease 273 19 Epidemiology, Surveillance, and Population Biology: Carriage Studies 293 20 Surveillance of Meningococcal Disease in Europe 313 21 Global Surveillance for Meningococcal Disease 333 22 Epidemiology of Meningococcal Disease in North America 341 23 Computational Methods for Meningococcal Population Studies 357 24 Clinical Studies: An Overview 375 25 Clinical Scoring Systems in Meningococcal Disease 411 26 Quantitative Detection of Bacterial Lipopolysaccharides in Clinical Specimens 427 27 Isolation and Analysis of Radiolabeled Meningococcal Endotoxin 441 28 Cytokine Measurement In Vivo and In Vitro 459 29 Cytokine Bioassays 487 30 Molecular Analysis of Gene-Polymorphisms Affecting the Host Response to Infection 499 31 Coagulation Studies 513 32 Complement Pathways and Meningococcal Disease: Diagnostic Aspects 529 33 Evaluation of New Treatments for Meningococcal Disease 549 34 Studies on the Effect of Neisserial Porins on Apoptosis of Mammalian Cells 587 35 Molecular Recognition Mechanisms of Meningococci: Identifying Receptor-Ligand Pairs Involved in Microbe-Host Interactions 599 36 Experimental Nasopharyngeal Colonization by Neisseria meningitidis Using Explant Organ Culture 621 37 Invasion of the Central Nervous System by Neisseria meningitidis 635 38 Interactions of Meningococci with Endothelium 649 39 A Promoter Probe Plasmid Based on Green Fluorescent Protein: A Strategy for Studying Meningococcal Gene Expression 663 40 Signature Tagged Mutagenesis 679 Index 693 |
|
|
|
|
|
|
|
|
µî·ÏµÈ ¼ÆòÀÌ ¾ø½À´Ï´Ù. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|