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Single Nucleotide Polymorphisms: Methods and Protocols |
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From Book News, Inc. Single nucleotide polymorphisms (SNPs) are markers that assist in clarifying the relationship between DNA sequence variation and susceptibility to disease. In this text, the inventors of various methods for SNP discovery and genotyping present detailed protocols for their use. Coverage includes techniques such as denaturing high-performance liquid chromatography (dHPLC), conformation-sensitive gel electrophoresis (CSGE), single-base extension approaches, and primer extension with mass spectrometry detection. Kwok is with the Cardiovascular Research Institute and Department of Dermatology at UC-San Francisco.Copyright 2004 Book News, Inc., Portland, OR
Book Info Univ. of California, San Francisco. Provides all the major SNP discovery and genotyping techniques in use, whether for using DNA diagnostics for identification; studying the genetic basis of human disease, or for molecular breeding programs in agriculture. Extended-outline and outline formats.
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