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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics 5th
 

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ÃâÆÇ»ç Oxford University Press
ÀúÀÚ Lauren Pecorino
Ãâ°£ÀÏ 2021/8
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ISBN 9780198833024 / 0198833024
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List Price £¤ 89.99
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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.

Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of new
targeted therapies, giving the reader a clear appreciation of how our understanding of the theory can be translated into new approaches for tackling the disease.

The new edition draws on the latest research in cancer biology, highlighting fundamental concepts and re-emphasising pre-existing concepts. The book features a variety of learning features--'Pause and think', 'How do we know that?', self-tests and activities--to help students engage with, and
master, the concepts presented. The emphasis is on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit.

Molecular Biology of Cancer is available for students and institutions to purchase in a variety of formats, and is supported by online resources.

The online resources include:

For students:
- Multiple choice questions
- Web links to additional cancer biology resources

For registered adopters of the book:
¡¤ Figures from the book, available to download
 
 
 
Chapter 1 : Introduction




Chapter 2 : The cancer genome




Chapter 3 : Regulation of gene expression




Chapter 4 : Growth factor signaling and oncogenes




Chapter 5 : The cell cycle




Chapter 6 : Tumor suppressor genes




Chapter 7 : Apoptosis




Chapter 8 : Cancer stem cells and the regulation of self-renewal and differentiation pathways: focus on colon cancer and leukemias



Chapter 9 : Metastasis




Chapter 10 : Angiogenesis




Chapter 11 : Reprogrammed metabolism and diet




Chapter 12 : Tumor immunology and immunotherapy




Chapter 13 : Inflammation, infection, and the microbiome




Chapter 14 : Strategies and tools for research and drug development
 
 
 
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