From Book News, Inc.
The 19 papers in this collection review the current status of pharmacogenomics studies of membrane transporters, classify transmembrane transport proteins, describe bioinformatics databases and tools, and provide guidelines for performing microarray experiments and data analysis. Several contributors outline the protocols for small angle x-ray scattering, fluorescence spectroscopy, reconstitution of transporters, working with Xenopus oocytes, and measuring intracellular pH. Other topics include molecular dynamics simulations of transporter proteins, imaging plasma membrane proteins by confocal microscopy, analysis of soluble sugar permease domains by solution NMR, and localization of high affinity amino acid transporters by immunocytochemistry.Copyright 2004 Book News, Inc., Portland, OR

Book Info
Text describes the methodologies for studying important proteins. Examines the databases and tools for bioinformatics analysis, provides guidelines for microarray experiments, and data analysis. Also includes state-of-the-art techniques for studying transporter pharmacogenomics. For researchers in pharmaceutical science.