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Fundamentals of Forensic DNA Typing, 1st Edition
 

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ÃâÆÇ»ç Academic Press
ÀúÀÚ John Butler
Ãâ°£ÀÏ 2009/8
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ISBN 9780123749994, 0123749999
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¡¡Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980¡¯s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining

¡¡DNA profiles and the issues involved when people use a database to search for close relatives.
Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable.


¡¡Key Features
¡¡¡¡¤ý¡¡Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect
¡¡¡¡¤ý¡¡Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout
¡¡¡¡¤ý¡¡Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
 
 
 
Foreword
Introduction
Acknowledgments
About the Author

Chapter 1 Overview and History of DNA Typing
Chapter 2 Basics of DNA Biology and Genetics
Chapter 3 Historical Methods
Chapter 4 Sample Collection, Storage, and Characterization
Chapter 5 DNA Extraction
Chapter 6 DNA Quantitation
Chapter 7 DNA Amplification (The Polymerase Chain Reaction)
Chapter 8 Short Tandem Repeat Markers
Chapter 9 Fundamentals of DNA Separation and Detection
Chapter 10 STR Genotyping and Data Interpretation
Chapter 11 Statistical Interpretation: Evaluating the Strength of Forensic DNA Evidence
Chapter 12 DNA Databases
Chapter 13 Quality Assurance
Chapter 14 Forensic Challenges: Degraded DNA, Mixtures, and LCN
Chapter 15 Additional Loci and Nonhuman DNA Testing
Chapter 16 Lineage Markers: Y Chromosome and mtDNA Testing
Chapter 17 Applications of DNA Typing
Chapter 18 Future Trends

Appendix 1 Glossary of Terms
Appendix 2 Useful Web Sites
Appendix 3 Probability and Statistics

Index

References are provided at the end of each chapter by subtopic (but without direct citation within the text).
High-profile cases and other interesting information are included as D.N.A. (Data, Notes, and Applications) boxes scattered throughout the book in the chapter pertaining to a particular subject.
 
 
 
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