Part of the highly regarded Diagnostic Pathology series, this updated volume by Drs. Dylan V. Miller and Monica P. Revelo is an ideal point-of-care reference for the accurate diagnosis of complex cardiovascular specimens. Concise, focused chapters, supported by tables, diagrams, radiographs, and photographs, provide essential information to keep you up to date with new cardiac devices, the increased use of molecular panels, WHO updates, and much more.
•Hundreds of images, including photomicrographs, spectacular gross images, electron micrographs, and vivid medical illustrations

•Separate sections on specimens encountered in the settings of biopsy, surgical resection, and autopsy
•Time-saving reference features include bulleted text, tables of diagnostic criteria, annotated images, and an extensive index
•Thoroughly updated content includes new cardiac devices that require pathologic evaluation; increasing volumes of established devices in surgical and autopsy specimens; the increasing use of molecular panels in the evaluation of cardiomyopathy, aortic diseases, sudden cardiac death, and myocarditis; and updates from an international consensus on cardiac tumor reporting (ICCR)

•A new chapter on TAVR (transcatheter) valves, plus updates to the chapters on prosthetic valves, LVADs, stents (including a description of 2 new methods of preparing sections that can be done in any histology lab), and more

•A new section, Autopsy Evaluation of Cardiovascular Disease, includes 9 chapters from the Diagnostic Pathology: Hospital Autopsy volume

•Updates from the new edition of the WHO blue book for cardiac tumors

•Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

SECTION 1: HEART, ENDOMYOCARDIAL BIOPSY

CONGENITAL/GENETIC

4 Endocardial Fibroelastosis Syndrome

6 Arrhythmogenic Cardiomyopathy

10 Fatty Acid Metabolic Disorders

12 Mitochondrial Myopathies

16 Muscular Dystrophies

20 Glycogen Storage Diseases

22 Fabry Disease, Heart

24 LAMP2 Mutation (Danon Disease)

ACQUIRED

26 Amyloid Deposition, Heart

32 Hemochromatosis, Heart

36 Anthracycline Cardiotoxicity

38 Catecholamine Cardiomyopathy

40 Cocaine Cardiotoxicity

INFLAMMATORY

42 Lymphocytic Myocarditis

46 Giant Cell Myocarditis

48 Eosinophilic (Loeffler) Myocarditis

52 Sarcoidosis, Heart

54 Acute Rheumatic Carditis

58 Eosinophilic Granulomatosis With Polyangiitis

60 Viral Myocarditis

62 Toxoplasmosis, Heart

64 Chagas Disease, Heart

68 Lyme Disease and Rickettsial Myocarditis

72 Lupus Erythematosus, Heart

TRANSPLANT REJECTION

78 Acute Cellular Transplant Rejection, Heart

84 Antibody-Mediated Transplant Rejection, Heart

90 Quilty Lesions

94 Previous Biopsy Sites, Heart Transplant

96 Posttransplant Lymphoproliferative Disorder, Heart

98 Harvesting Injury/Acute Ischemia, Heart

SECTION 2: HEART, RESECTION

HEART EXPLANT

104 Hypertrophic Cardiomyopathy

108 Idiopathic Dilated Cardiomyopathy

112 Ischemic Heart Disease

116 Overview of Coronary Artery Stents

120 Cardiac Allograft Vasculopathy

126 Radiation Injury, Heart

128 Cardiac Conduction System Disease

136 Ventricular Assist Devices

140 Approach to Cardiomyopathy (Worksheet)

142 Approach to Cardiomyopathy Diagnosis

SECTION 3: HEART, TUMORS

BENIGN

150 Cardiac Myxoma

156 Papillary Fibroelastoma

160 Cardiac Rhabdomyoma

164 Cardiac Fibroma

168 Ectopic Tissues, Heart

170 Lipomatous Hypertrophy of the Atrial Septum

MALIGNANT

172 Cardiac Lymphoma

174 Cardiac Angiosarcoma

178 Cardiac Sarcoma, Other

182 Cardiac Metastases

SECTION 4: CARDIAC VALVES, NATIVE

AORTIC

190 Unicommissural Aortic Valve

194 Bicuspid Aortic Valve

198 Senile Calcific Aortic Stenosis

200 Discrete Membranous Subaortic Stenosis

MITRAL

202 Myxomatous Mitral Valve Disease

206 Rheumatic Heart Disease

TRICUSPID

210 Carcinoid Heart Disease

214 Ebstein Anomaly

PULMONARY

216 Congenital Pulmonary Stenosis

ENDOCARDITIS

218 Endocarditis, Native Valve

222 Nonbacterial Thrombotic Endocarditis

SECTION 5: CARDIAC VALVES

PROSTHETIC

228 Leaflet Degeneration, Prosthetic Valves

232 Thrombosis of Prosthetic Valves

234 Endocarditis, Prosthetic Valve

240 Mechanical Heart Valve Prostheses: Modes of Failure

242 Catheter-Deployed Valve Therapies

SECTION 6: PERICARDIUM

INFLAMMATORY

248 Acute Pericarditis

252 Constrictive Pericarditis

254 Tuberculous Pericarditis

TUMORS

256 Lymphoma, Pericardium

258 Metastatic Tumor, Pericardium

262 Mesothelioma, Pericardium

266 Mesothelial/Monocytic Incidental Cardiac Excrescence (MICE)

SECTION 7: VASCULAR DISEASE

ENDARTERECTOMY/ATHERECTOMY/THROM BECTOMY

270 Overview of Peripheral Vascular Specimens

276 Thromboembolus, Vascular

THORACIC AORTA

280 Aortic Degenerative Diseases

288 Genetic Diseases of the Aorta

292 Noninfectious Aortitis

296 Takayasu Arteritis

300 Aortic Dissection

304 Aortic Coarctation

ABDOMINAL AORTA

308 Aortic Atherosclerosis and Complications

314 Chronic Periaortitis and IgG4-Related Disease

316 Mycotic Aneurysm

CORONARY ARTERIES

320 Atherosclerosis, Coronary

324 Coronary Artery Dissection

326 Kawasaki Disease

TEMPORAL ARTERIES

332 Giant Cell/Temporal Arteritis Monica P. Revelo, MD, PhD

PERIPHERAL VESSELS

336 Buerger Disease (Thromboangiitis Obliterans)

340 Fibromuscular Dysplasia

346 Segmental Arterial Mediolysis

348 Mönckeberg Medial Calcific Sclerosis

350 Behçet Disease

354 Infectious Vasculitis

360 Lymphocytic Venulitis

362 Varicosities

364 Hypertensive Renovascular Diseases

VASCULAR TISSUE GRAFTS

368 Vascular Graft Pseudoaneurysm

SECTION 8: VASCULAR TUMORS

BENIGN

374 Hemangioma

384 Angiomyolipoma

388 Glomus Tumor

396 Cystic Lymphangioma

398 Arteriovenous Malformations

MALIGNANT

402 Epithelioid Hemangioendothelioma

406 Kaposi Sarcoma

412 Angiosarcoma

SECTION 9: AUTOPSY

CARDIAC

420 Coronary Artery Bypass Grafting

424 Valve Replacement (Including Transcatheter)

430 Infective Endocarditis

434 Ventricular Assist Device Insertion

438 Heart Transplant

VASCULAR

444 Thoracic Aortic Aneurysm Repair

450 Abdominal Aortic Aneurysm

452 Cerebral Aneurysm and Vascular Malformation