Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and its Impact on Human Reproductive Medicine shows how genomics and various omics technologies are already significantly aiding fertility specialists and clinicians in counseling couples towards pregnancy success, characterizing patients, and informing embryo selection. Information derived from omics approaches and bioinformatics are coupled in order to offer an in-depth view of the human reproduction system. A diverse range of chapters from international experts demonstrate the complex relationship between genomics, epigenomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying within these singular pathways specific genomic and molecular factors of translational impact. With this book Editors Jaime Gosálvez and José Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

INTRODUCTION
1. Human Genome Projects: the starting point
2. Classic spermiogram: still informative?

GENOMICS
3. Genetics variations and human infertility
4. Preconceptional analysis of monogenic diseases
5. Genetic selection of the human embryos: from FISH to NGS, past and future
6. Non-invasive prenatal diagnosis
7. Genetic point mutations in male infertility
8. Telomere length and idiopathic infertility

FUNCTIONAL GENOMICS OR TRANSCRIPTOMICS
9. The molecular signature of the endometrial receptivity: research and clinical application
10. Gene expression of cumulus cells: an indirect diagnosis of oocyte quality
11. Variations in the gene expression of the sperm: clinical use
12. Transcriptomic of the embryo and embryo viability: the inner cell mass and the trophoblast
13. Altered gene expression profiles associated with infertility
14. Prostasomes and fertility
15. Small RNAs in human sperm

PROTEOMICS AND METABOLOMICS
16. Non-invasive methods of embryo selection
17. Proteomics and metabolomics studies and clinical outcomes

EPIGENOMICS
18. Epigenetics in spermatogenesis
19. Epigenetics, spermatogenesis and male infertility
20. Changes in DNA methylation related with male infertility
21. Epigenomics of the embryo: in vivo and in vitro evidences
22. Artificial Spermatoza

COMPUTATIONAL BIOLOGY
23. Computational approaches in Reproductomics

CONCLUSIONS
24. Year 2050: The “-Omics” technologies and Personalized Assisted Reproduction