With all the complex issues of acceptance or rejection of a transplanted organ, immunology is a key subject for all transplantation clinicians. During recent years, there has been an explosion of research and knowledge in this area. Produced in association with the American Society of Transplantation, and written by experts within the field, Transplant Immunology provides a comprehensive overview of the topic in relation to clinical transplantation. Starting with the basic functionality of the immune system, it then moves on to cover the very latest developments in immunosupressive drugs and protocols, as well as a look at all emerging technologies in the field.

Key chapters include:
ㆍTransplant-related complications
ㆍImmune responses to transplants
ㆍEmerging issues in transplantation
ㆍBiomarkers of Allograft rejection and tolerance
ㆍCells and the principles of immune responses

In full colour throughout, over 100 outstanding diagrams support the text, all figures being fully downloadable via the book's companion website. The result is an essential tool for all those responsible for managing patients awaiting and undergoing organ transplantation, including transplant surgeons and clinicians, immunologists and researchers.

List of Contributors

Foreword
Preface

1 Tissues and Organs of the Immune System
Isam W. Nasr, Qiang Zeng, and Fadi G. Lakkis

2 Cells of the immune system
Jonathan S. Bromberg, Jason R. Lees, Tonya J. Webb, Yaozhong Ding and Agnes M. Azimzadeh

3 Soluble Mediators of Cell-Cell Communication in the Immune System
Charles A. Su, William M. Baldwin III, and Robert L. Fairchild

4 Costimulatory molecules
Maria-Luisa Alegre and Anita S. Chong

5 Major Histocompatibility Complex
Raja Rajalingam, Qiuheng Zhang, J. Michael Cecka and Elaine F. Reed

6 T cells and the principles of immune responses
Jonathan S. Maltzman, Angus Thomson, and David M. Rothstein

7 Ischemia and Reperfusion Injury
Yuan Zhai, Yoichiro Uchida, Bibo Ke, Haofeng Ji, Jerzy W. Kupiec-Weglinski

8 Immune Responses to Transplants
Denise J. Lo and Allan D. Kirk

9 Principles of Hematopoietic Cell Transplantation
Sung Choi and Pavan Reddy

10 Therapeutic approaches to organ transplantation
Philip F. Halloran, Chatchai Kreepala, Gunilla Einecke, Alexandre Loupy, and Joana Sellarés

11 Organ specific features in clinical transplantation
Roslyn B. Mannon

12 Transplant-related complications
Anil Chandraker and Leonardo V. Riella

13 Biomarkers of Allograft Rejection and Tolerance
Choli Hartono, Thangamani Muthukumar, and Manikkam Suthanthiran

14 Emerging issues in transplantation
Rupert Oberhuber, Guangxiang Liu, Timm Heinbokel and Stefan G. Tullius

15 New Frontiers and New Technologies
Haval Shirwan, Yiming Huang, Kadiyala Ravindra, and Suzanne T. Ildstad

16 Experimental models in discovery and translational studies
Andrew B. Adams, William H. Kitchens, Kenneth A. Newell

Index