The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems throughout the chapter, with a ton of practice problems at the end. Answers for the practice problems are in the back, but not detailed like the sample problems)

*Changes in the 3/e includes:

*All chapters updated and revised, as needed, including critical new references

*Antibiotic individualization and monitoring sections increases use of pharmacodynamic parameters (Cmax/MIC, AUC24/MIC, Time above MIC) in addition to pharmacokinetic parameters to adjust dosages

*Anticonvulsants section includes 5 new agents (Fosphenytoin, Lamotrigine, Levetiracetam, Oxcarbazepine, Eslicarbazepine)

*Immunosuppressants section includes 1 new agent (Sirolimus),



About the Book

Text focuses on the latest standardized techniques and approaches to patient-specific dosing and provides up-to-date information on more recently moniotored drugs.



Features

Clear, useful coverage of drug dosing and drug monitoring Clear and concise summary of pharmacokinetic and pharmacodynamic concepts

Practical help with calculations and equations

Focus on the latest standardized techniques and approaches to patient-specific dosing

Up-to-date information on more recently monitored drugs

Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure

All the information practitioners need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants

Full coverage of drugs such as Aminoglycosides, Vancomycin, Digoxin, Phenytoin, Carbamazepine, Theophylline, Cyclosporine, Tacrolimus, and Lithium Student friendly approach to teaching pharmacokinetics--sample problems embedded into the text to allow for students to apply what they are learing.

Part I. Basic Concepts
Chapter 1. Clinical Pharmacokinetic and Pharmacodynamic Concepts
Chapter 2. Clinical Pharmacokinetic Equations and Calculations
Chapter 3. Drug Dosing in Special Populations: Renal and Hepatic Disease, Dialysis, Heart Failure, Obesity, and Drug Interactions

Part II. Antibiotics
Chapter 4. The Aminoglycoside Antibiotics
Chapter 5. Vancomycin

Part III. Cardiovascular Agents
Chapter 6. Digoxin
Chapter 7. Lidocaine
Chapter 8. Procainamide/N-Acetyl Procainamide
Chapter 9. Quinidine

Part IV. Anticonvulsants
Chapter 10. Phenytoin
Chapter 11. Carbamazepine
Chapter 12. Valproic Acid
Chapter 13. Phenobarbital/Primidone
Chapter 14. Ethosuximide
Chapter 15. Lamotrigine
Chapter 16. Levetiracetam
Chapter 17. Oxcarbazepine


Part V. Immunosuppressants
Chapter 18. Cyclosporine
Chapter 19. Tacrolimus
Chapter 20. Sirolimus


Part VI. Other Drugs
Chapter 21. Lithium
Chapter 22. Theophylline