From Book News, Inc.
The second edition of this text retains integration of molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems, yet streamlines the material to focus on cell membrane receptors and their immediate signal transducers. Two new chapters cover G-proteins and tyrosine kinases as signal transductors, and there is more material on the molecular structure of receptors, reflecting recent advances in the field. Foreman is affiliated with the Department of Pharmacology at University College London, UK. Johansen is affiliated with the Department of Physiology and Pharmacology at the University of Southern Denmark.Book News, Inc., Portland, OR

Book Description
The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation.This edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions.The book contains over one hundred useful diagrams and tables to aid illustration of concepts and a helpful appendix explaining the simple mathematics used in the text. A time-saving resource and comprehensive textbook, Textbook of Receptor Pharmacology, Second Edition provides in-depth, up-to-date coverage of this still rapidly expanding research area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.

Book Info
Univ. College, London, UK. Introductory text on receptor pharmacology provides in-depth coverage of the rapidly expanding research area. Features more than 100 diagrams and tables, introductions to the various approaches in the study of drug receptors, and presents information from an international group of experts. Previous edition: c1996.

Drug-Receptor Interactions
Classical Approaches to the Study of Drug-Receptor Interactions, D. H. Jenkinson

Molecular Structure of Receptors
Molecular Structure and Function of 7TM G-Protein Coupled Receptors, T. W. Schwartz and B. Holst
The Structure of Ligand-Gated Ion Channels, J. Egebjerg
Molecular Structure of Receptor Tyrosine Kinases, S. Gammeltoft New!

Ligand Binding Studies of Receptors
Direct Measurement of Drug Binding to Receptors, D. G. Haylett

Transduction of the Receptor Signal
Receptors Linked to Ion Channels: Mechanisms of Activation and Block, A. J. Gibb
G Proteins, D. A. Brown New!
Signal Transduction through Protein Tyrosine Kinases, I. Kramer

Receptors as Pharmaceutical Targets
Receptors as Pharmaceutical Targets, J. W. Black

Index