Meet the increasing need for effective brain tumor management with the highly anticipated revision of Brain Tumors by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy. You’ll also have easy access to the complete contents online, with links to PubMed and a downloadable image library, at www.expertconsult.com.
•Benefit from the knowledge and experience of Drs. Andrew H. Kaye and Edward R. Laws, globally recognized experts in the field of neurosurgery, as well as many other world authorities.
•Access the complete searchable contents online at www.expertconsult.com, with links to PubMed and a downloadable image library.

•Stay up to date with the latest developments in the field, including management of

malignant gliomas; functional brain mapping; neurogenetics and the molecular biology of brain tumors; biologic and gene therapies; and much more.

Apply the expert’s best practices with their key points .

The expert guidance of Drs. Kaye and Laws allows you to effectively deal with the increasing incidence of brain tumors, from diagnosis to surgical and radiotherapeutic management.




















Access the complete searchable contents online at www.expertconsult.com, with links to PubMed and a downloadable image library.




Stay up to date with the latest developments in the field, including management of




malignant gliomas; functional brain mapping; neurogenetics and the molecular biology of brain tumors; biologic and gene therapies; and much more.



Apply the expert's best practices with their key points .

1 Historical perspective 1





2 Stem cells and progenitor cell lineages in the central nervous system 6








3 Classification and pathogenesis of brain tumors 36








4 Epidemiology of brain tumors 59








5 Neurogenetics and the molecular biology of human brain tumors 83








6 Biologic therapy for malignant glioma 102








7 Gene therapy for human brain tumors 114








8 Immunology of brain tumors and implications for immunotherapy 125








9 Histopathology of brain tumors 138








10 Advanced imaging of brain tumors 188








11 Neuro-ophthalmology of brain tumors 214








12 Epilepsy associated with brain tumors 237








13 Anesthesia and intensive care management of patients with brain tumors 249








14 Surgical principles in the management of brain tumors 282








15 Radiosurgery and radiotherapy for brain tumors 296








16 Clinical trials and chemotherapy 306








17 Mouse models for brain tumor therapy 316








18 Management of brain tumors in the pediatric patient 329








19 Management of recurrent gliomas and meningiomas 347








20 Low-grade astrocytomas 372








21 Glioblastoma and malignant astrocytoma 384








22 Oligodendroglioma 408








23 Brainstem tumors 424








24 Intracranial ependymomas 435








25 Choroid plexus tumors 450








26 Uncommon glial tumors 462








27 Medulloblastoma and primitive neuroectodermal tumors 503








28 Acoustic neurinoma (vestibular schwannoma) 518








29 Other schwannomas of cranial nerves 570








30 Brain tumors associated with neurofibromatosis 588








31 Meningiomas 600








32 Meningeal hemangiopericytomas 630








33 Meningeal sarcomas 638








34 Pineal cell and germ cell tumors 646








35 Non-functional pituitary tumors 672








36 Diagnostic considerations and surgical results for hyperfunctioning pituitary adenomas 692








37 Chordomas and chondrosarcomas of the skull base 723








38 Glomus jugulare tumors 743








39 Carcinoma of the paranasal sinuses 750








40 Esthesioneuroblastoma: management and outcome 767








41 Primary central nervous system lymphoma 779








42 Craniopharyngiomas 807








43 Dermoid, epidermoid, and neurenteric cysts 831








44 Colloid cysts 849








45 Metastatic brain tumors 864